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Index > Protein center > ALDOB(Gene name) > Human
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  • ALDOB (Gene name),
  • Fructose-bisphosphate aldolase B (Protein name ),  ALDOB_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ALDOB(ALDB);
    Protein name:
    Fructose-bisphosphate aldolase B;
    Alternative:
    Liver-type aldolase;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homotetramer.
    Function:
    N/A
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    364
    Sequence:
    50:
    MAHRFPALTQ | EQKKELSEIA | QSIVANGKGI | LAADESVGTM | GNRLQRIKVE | 
    100:
    NTEENRRQFR | EILFSVDSSI | NQSIGGVILF | HETLYQKDSQ | GKLFRNILKE | 
    150:
    KGIVVGIKLD | QGGAPLAGTN | KETTIQGLDG | LSERCAQYKK | DGVDFGKWRA | 
    200:
    VLRIADQCPS | SLAIQENANA | LARYASICQQ | NGLVPIVEPE | VIPDGDHDLE | 
    250:
    HCQYVTEKVL | AAVYKALNDH | HVYLEGTLLK | PNMVTAGHAC | TKKYTPEQVA | 
    300:
    MATVTALHRT | VPAAVPGICF | LSGGMSEEDA | TLNLNAINLC | PLPKPWKLSF | 
    350:
    SYGRALQASA | LAAWGGKAAN | KEATQEAFMK | RAMANCQAAK | GQYVHTGSSG | 
    364:
    AASTQSLFTA | CYTY
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    String:
    SMR:
    UniGene:
    MIM:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Fructose-bisphosphate aldolase B
    Cat.:
    E0622h
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    96T
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    ELISA Kit for Human Fructose-bisphosphate aldolase B
    Cat.:
    E0622m
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    96T
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    ELISA Kit for Human Fructose-bisphosphate aldolase B
    Cat.:
    E0622c
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    96T
    ELISA Kit for Human Fructose-bisphosphate aldolase B
    Cat.:
    E0622r
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    Packing:
    96T
    ELISA Kit for Human Fructose-bisphosphate aldolase B
    MSDS:
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    ELISA Kit for Human Fructose-bisphosphate aldolase B
    Cat.:
    E0622b
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    Packing:
    96T
    CLIA Kit for Human Fructose-bisphosphate aldolase B
    Cat.:
    U0622m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Fructose-bisphosphate aldolase B
    Cat.:
    U0622h
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Fructose-bisphosphate aldolase B
    Cat.:
    U0622c
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    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Fructose-bisphosphate aldolase B
    Cat.:
    U0622r
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    Please sign in first.
    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Fructose-bisphosphate aldolase B
    MSDS:
    Please sign in first.
    CLIA Kit for Human Fructose-bisphosphate aldolase B
    Cat.:
    U0622b
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Fructose-bisphosphate aldolase B
    Polyclonal Antibody for Human Fructose-bisphosphate aldolase B
    Polyclonal Antibody for Human Fructose-bisphosphate aldolase B
    Cat.:
    P0622Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Fructose-bisphosphate aldolase B
    Polyclonal Antibody for Human Fructose-bisphosphate aldolase B
    Cat.:
    P0622Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Fructose-bisphosphate aldolase B
    Cat.:
    P0622Rb-m
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Fructose-bisphosphate aldolase B
    Monoclonal Antibody for Human Fructose-bisphosphate aldolase B
    Monoclonal Antibody for Human Fructose-bisphosphate aldolase B
    Monoclonal Antibody for Human Fructose-bisphosphate aldolase B
    Monoclonal Antibody for Human Fructose-bisphosphate aldolase B
    Monoclonal Antibody for Human Fructose-bisphosphate aldolase B
    Protein for Human Fructose-bisphosphate aldolase B
    Protein for Human Fructose-bisphosphate aldolase B
    Protein for Human Fructose-bisphosphate aldolase B
    Protein for Human Fructose-bisphosphate aldolase B
    Protein for Human Fructose-bisphosphate aldolase B
    Protein for Human Fructose-bisphosphate aldolase B

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Isolation and nucleotide sequence of a full-length cDNA coding for aldolase B from human liver."
      Paolella G. , Santamaria R. , Izzo P. , Costanzo P. , Salvatore F.
      Nucleic Acids Res.12:7401-7410(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Human aldolase isozyme gene: the structure of multispecies aldolase B mRNAs."
      Sakakibara M. , Mukai T. , Yatsuki H. , Hori K.
      Nucleic Acids Res.13:5055-5069(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Complete amino acid sequence for human aldolase B derived from cDNA and genomic clones."
      Rottmann W.H. , Tolan D.R. , Penhoet E.E.
      Proc. Natl. Acad. Sci. U.S.A.81:2738-2742(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA]
    4. 4.
      "Human aldolase B gene: characterization of the genomic aldolase B gene and analysis of sequences required for multiple polyadenylations."
      Mukai T. , Yatsuki H. , Arai Y. , Joh K. , Matsuhashi S. , Hori K.
      J. Biochem.102:1043-1051(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    5. 5.
      "Characterization of the human aldolase B gene."
      Tolan D.R. , Penhoet E.E.
      Mol. Biol. Med.3:245-264(1986) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    6. 6.
      "DNA sequence and analysis of human chromosome 9."
      Humphray S.J. , Oliver K. , Hunt A.R. , Plumb R.W. , Loveland J.E. , Howe K.L. , Andrews T.D. , Searle S. , Hunt S.E. , Scott C.E. , Jones M.C. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Ashwell R.I.S. , Babbage A.K. , Babbage S. , Bagguley C.L. , more...
      Nature429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      "Construction and expression of human aldolase A and B expression plasmids in Escherichia coli host."
      Sakakibara M. , Takahashi I. , Takasaki Y. , Mukai T. , Hori K.
      Biochim. Biophys. Acta1007:334-342(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-33 AND 357-364
    9. 9.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 238-364
    10. 10.
      "Novel interaction partners of Bardet-Biedl syndrome proteins."
      Oeffner F. , Moch C. , Neundorf A. , Hofmann J. , Koch M. , Grzeschik K.H.
      Cell Motil. Cytoskeleton65:143-155(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH BBS1; BBS2; BBS4 AND BBS7;SUBCELLULAR LOCATION
    11. 11.
      "The structure of human liver fructose-1,6-bisphosphate aldolase."
      Dalby A.R. , Tolan D.R. , Littlechild J.A.
      Acta Crystallogr. D57:1526-1533(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.5 ANGSTROMS)
    12. 12.
      "Molecular basis of hereditary fructose intolerance: mutations and polymorphisms in the human aldolase B gene."
      Tolan D.R.
      Hum. Mutat.6:210-218(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW ON VARIANTS
    13. 13.
      "Catalytic deficiency of human aldolase B in hereditary fructose intolerance caused by a common missense mutation."
      Cross N.C.P. , Tolan D.R. , Cox T.M.
      Cell53:881-885(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HFI PRO-150
    14. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HFI ASP-175
    15. 15.
      "A partially active mutant aldolase B from a patient with hereditary fructose intolerance."
      Brooks C.C. , Tolan D.R.
      FASEB J.8:107-113(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HFI ARG-135
    16. 16.
      "Diverse mutations in the aldolase B gene that underlie the prevalence of hereditary fructose intolerance."
      Ali M. , Cox T.M.
      Am. J. Hum. Genet.56:1002-1005(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT ARG-148
    17. 17.
      "Identification of a novel mutation (Leu 256-->Pro) in the human aldolase B gene associated with hereditary fructose intolerance."
      Ali M. , Sebastio G. , Cox T.M.
      Hum. Mol. Genet.3:203-204(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HFI PRO-257
    18. 18.
      "A new aldolase B variant, N334K, is a common cause of hereditary fructose intolerance in Yugoslavia."
      Cross N.C.P. , Stojanov L.M. , Cox T.M.
      Nucleic Acids Res.18:1925-1925(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT HFI LYS-335
    19. 19.
      "Screening for hereditary fructose intolerance mutations by reverse dot-blot."
      Lau J. , Tolan D.R.
      Mol. Cell. Probes13:35-40(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HFI PRO-150; ASP-175; PRO-257; TRP-304; LYS-335 AND VAL-338
    20. 20.
      "Functional and molecular modelling studies of two hereditary fructose intolerance-causing mutations at arginine 303 in human liver aldolase."
      Santamaria R. , Esposito G. , Vitagliano L. , Race V. , Paglionico I. , Zancan L. , Zagari A. , Salvatore F.
      Biochem. J.350:823-828(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HFI GLN-304 AND TRP-304;CHARACTERIZATION OF VARIANTS HFI GLN-304 AND TRP-304;KINETIC PARAMETERS
    21. 21.
      "Molecular analysis of the aldolase B gene in patients with hereditary fructose intolerance from Spain."
      Sanchez-Gutierrez J.C. , Benlloch T. , Leal M.A. , Samper B. , Garcia-Ripoll I. , Feliu J.E.
      J. Med. Genet.39:E56-E56(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HFI PRO-150; ASP-175; ARG-185 AND LYS-335
    22. 22.
      "Six novel alleles identified in Italian hereditary fructose intolerance patients enlarge the mutation spectrum of the aldolase B gene."
      Esposito G. , Santamaria R. , Vitagliano L. , Ieno L. , Viola A. , Fiori L. , Parenti G. , Zancan L. , Zagari A. , Salvatore F.
      Hum. Mutat.24:534-534(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HFI THR-74; 120-ASN-LYS-121 DEL; PRO-150; ASP-175; PHE-222; PRO-229; PRO-257; LYS-335 AND VAL-338;CHARACTERIZATION OF VARIANTS HFI THR-74; PHE-222 AND PRO-229
    23. 23.
      "The spectrum of aldolase B (ALDOB) mutations and the prevalence of hereditary fructose intolerance in Central Europe."
      Santer R. , Rischewski J. , von Weihe M. , Niederhaus M. , Schneppenheim S. , Baerlocher K. , Kohlschuetter A. , Muntau A. , Posselt H.-G. , Steinmann B. , Schneppenheim R.
      Hum. Mutat.25:594-594(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HFI PRO-150; ASP-175; ARG-178; PRO-284 AND LYS-335
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